Meat and Nicotinamide: A Causal Role in Human Evolution, History, and Demographics

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URL: https://www.semanticscholar.org/paper/Meat-and-Nicotinamide%3A-A-Causal-Role-in-Human-and-Williams-Hill/9035affefd17d929ae006c83984f7eb51b063c21

Journal: International Journal of Tryptophan Research

Publication Date: 03/2017

Summary: Hunting for meat was a critical step in all animal and human evolution. A key brain-trophic element in meat is vitamin B3 / nicotinamide. The supply of meat and nicotinamide steadily increased from the Cambrian origin of animal predators ratcheting ever larger brains. This culminated in the 3-million-year evolution of Homo sapiens and our overall demographic success. We view human evolution, recent history, and agricultural and demographic transitions in the light of meat and nicotinamide intake. A biochemical and immunological switch
is highlighted that affects fertility in the u2018de novou2019 tryptophan-to-kynurenine-nicotinamide u2018immune toleranceu2019 pathway. Longevity relates to nicotinamide adenine dinucleotide consumer pathways. High meat intake correlates with moderate fertility, high intelligence, good health, and longevity with consequent population stability, whereas low meat/high cereal intake (short of starvation) correlates with high fertility, disease, and population booms and busts. Too high a meat intake and fertility falls below replacement levels. Reducing variances in meat consumption might help stabilise population growth and improve human capital.

Key Takeaways

Meat is rich in vitamin B3 (nicotinamide). Meat Rich diets correlate with moderate levels of fertility, high intelligence, good overall health, and longevity. Low meat diets high in cereal result in increased fertility, but correlate with disease, and sharp rises and falls in population. Steady higher levels of meat intake may be helpful in maintaining healthy populations.

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