Ketogenic diet and Neuroinflammation

Share This Post

URL: https://pubmed.ncbi.nlm.nih.gov/32987244/
Journal: Epilepsy Research
Publication Date: 09/2020
Summary: The high-fat, low-carbohydrate ketogenic diet (KD) is an established treatment for drug-resistant epilepsy with a proven efficacy. The KD is being explored for Febrile Infection-Related Epilepsy Syndrome (FIRES) and epileptic encephalopathies. There is growing evidence that KD works by targeting dysregulated adaptive and innate immunity that occurs in drug-resistant epilepsy and in refractory status epilepticus. Beyond epilepsy, there are yet additional potential uses in neurological disorders because KD appears to have the broad anti-inflammatory and neuroprotective properties. The KD exerts anti-inflammatory action against a variety of experimental models of neurological disorders including multiple sclerosis, Parkinson’s disease, pain, and spinal cord injury. Anti-inflammatory action of KD appears to be mediated by multiple mechanisms. Ketones bodies, caloric restriction, polyunsaturated fatty acids and gut microbiota modifications might be involved in the modulation of inflammation by the KD.

Share This Post

Subscribe To Our Newsletter

Get Fun Carnivore Updates and inspirations

Leave a Comment

Your email address will not be published.

More To Explore

Ketogenic diet for weight loss

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371871/Journal: Canadian Family PhysicianPublication Date: 12/2018Summary: Ketogenic diets can help patients lose about 2 kg more than low-fat diets do at 1 year, but higher-quality studies show no difference. Weight loss peaks at about 5 months but is often not sustained. Individual weight change can vary from losing 30 kg to gaining 10 kg

Vitamin D as a promising anticancer agent

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081446/Journal: Indian Journal of PharmacologyPublication Date: 04/2011Summary: Presence of vitamin D receptors in noncalcemic tissues and subsequent identification of its involvement in growth factor(s)-mediated cellular function suggested its probable beneficial role in genesis, progression and survival of cancerous growths. Data collected from both in vitro and in vivo studies are highly optimistic regarding its

Do You Want To Achieve your Optimal Health?

Join us for a free 30-date trial. Cancel Anytime.