Ketogenic Diet and Health

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URL: https://www.lidsen.com/journals/icm/icm-06-02-015
Journal: OBM Integrative and Complementary Medicine
Publication Date: 04/2021
Summary: Carbohydrate-restricted ketogenic diets (KD) were introduced in the mid-19th century as a weight loss method with a resurgence of its use in epilepsy treatment in the 1920’s. Research conducted over the last several years provides evidence that KD’s can confer beneficial effects for several chronic metabolic diseases, including obesity, type-2 diabetes, and polycystic ovary syndrome. In recent years, emerging evidence suggests KD’s may also have therapeutic benefits for some cancers and for neurological conditions such as Alzheimer’s disease, Parkinson’s’ disease, multiple sclerosis, traumatic brain injury, and spinal cord injury. Finally, as the physiological mechanisms by which a KD operates become increasingly understood, we speculate that several other health conditions (e.g., autism, cystic fibrosis, COVID-19) that may improve from consuming a KD. The potential to reduce or eliminate long-term pharmaceutical treatments and their potential adverse effects by modifying diet patterns justifies additional research, particularly rigorously conducted clinical trials with long-term follow-up. This brief review describes a selection of the recent studies of KD as applied to chronic metabolic diseases, and provides an estimate of the quality of the evidence for KD’s effects. We also describe and appraise some of the risks and misconceptions attributed to KD which may limit the widespread use of KD’s among physicians and healthcare providers.

Key Takeaways

Since the introduction of the ketogenic diet in the 1920's as a treatment for epilepsy, the diet has proven to show many metabolic benefits that prove useful in the treatment of diseases such as type 2 diabetes, PCOS, obesity, Alzheimer's, Parkinson's, multiple sclerosis, and brain/spinal injuries. This dietary pattern is being studied more and more, and the fact that this dietary treatment can reduce or prevent the use of pharmaceutical medication warrants more rigorous studies. In addition, this dietary pattern may prove useful for other health conditions as well from autism to COVID-19. The ketogenic diet may be pivotal in the future of medicine.

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Ketogenic Diet and Health

URL: https://www.lidsen.com/journals/icm/icm-06-02-015Journal: OBM Integrative and Complementary MedicinePublication Date: 04/2021Summary: Carbohydrate-restricted ketogenic diets (KD) were introduced in the mid-19th century as a weight loss method with a resurgence of its use in epilepsy treatment in the 1920’s. Research conducted over the last several years provides evidence that KD’s can confer beneficial effects for several chronic metabolic

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