Women’s health

Peer-Reviewed Scientific Articles​

Effects of a ketogenic diet in overweight women with polycystic ovary syndrome

URL: https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-020-02277-0

Journal: Journal of Translational Medicine

Publication Date: 02/2020

Summary: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during reproductive age. It is characterized clinically by oligo-ovulation or anovulation, hyperandrogenism, and the presence of polycystic ovaries. It is associated with an increased prevalence of metabolic syndrome, cardiovascular disease and type 2 diabetes. The onset of PCOS has been associated to several hereditary and environmental factors, but insulin resistance plays a key pathogenetic role. We sought to investigate the effects of a ketogenic diet (KD) on women of childbearing age with a diagnosis of PCOS. Fourteen overweight women with diagnosis of PCOS underwent to a ketogenic Mediterranean diet with phyoextracts (KEMEPHY) for 12 week. Changes in body weight, body mass index (BMI), fat body mass (FBM), lean body mass (LBM), visceral adipose tissue (VAT), insulin, glucose, HOMA-IR, total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglycerides (TGs), total and free testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH); dehydroepiandrosterone sulfate (DHEAs), estradiol, progesterone, sex hormone binding globulin (SHBG) and Ferriman Gallwey score were evaluated. After 12 weeks, anthropometric and body composition measurements revealed a significant reduction of body weight (− 9.43 kg), BMI (− 3.35), FBM (8.29 kg) and VAT. There was a significant, slightly decrease of LBM. A significant decrease in glucose and insulin blood levels were observed, together with a significant improvement of HOMA-IR. A significant decrease of triglycerides, total cholesterol and LDL were observed along with a rise in HDL lev- els. The LH/FSH ratio, LH total and free testosterone, and DHEAS blood levels were also significantly reduced. Estradiol, progesterone and SHBG increased. The Ferriman Gallwey Score was slightly, although not significantly, reduced. Our results suggest that a KD may be considered as a valuable non pharmacological treatment for PCOS. Longer treatment periods should be tested to verify the effect of a KD on the dermatological aspects of PCOS

Key Takeaways

Polycystic Ovarian Syndrome occurs in women with a genetic predisposition that is triggered by obesity and insulin resistance. This results in a hormonal change resulting in excess male sex hormones, cysts in the ovaries, and increased hair growth on face, chest, and other areas. When a group of women with PCOS were placed on a mediterranean ketogenic diet, they saw a reduction in body fat, body weight, insulin resistance, and blood lipids. They also saw a significant normalization in hormone levels with decreases in male sex hormones and increases in female sex hormones.

Ketogenic Diets May Be A Useful Non-Pharmocologic Treatment For PCOS

The Effects of a High-Protein Diet on Bone Mineral Density in Exercise-Trained Women: A 1-Year Investigation

URL: https://www.mdpi.com/2411-5142/3/4/62

Journal: Journal of Functional Morphology and Kinesiology

 Publication Date: 12/2018

 Summary: Exercise-trained female subjects that consume a diet that is approximately three times greater than the RDA for protein experience no harmful effects on bone mineral density or content. Nor were there any harmful effects on renal function.

Key Takeaways

In female subjects who exercised regularly, high protein diets that are 3x the recommended daily value did not negatively affect the bones or kidney function.

High Protein Diets Will Hurt My Kidneys Right? Wrong!

Vitamin D deficiency in mothers, neonates and children

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/28179126/

Journal: The Journal of Steroid Biochemistry and Molecular Biology

Publication Date: 01/2018

Summary: Vitamin D deficiency mainly occurs if strict vegetarian diet is followed as mostly the source of vitamin D is animal based. Low vitamin D levels results in increased possibility of gestational diabetes among pregnant women, low birth weight and pre-eclampsia in infants, and mothers may suffer bone impairment, osteoporosis, hypocalcaemia, and hypertension. Vitamin D deficiency is directly linked with severe complication in mothers and neonates, causing rickets, poor fetal growth and infantile eczema in neonates.

Key Takeaways

Strict vegan diets can lead to low Vitamin D, which can result in gestational diabetes, low birth weight, and high blood pressure during pregnancy. Mothers can also experience low calcium and osteoporosis. Newborns may also experience rickets, poor growth, and eczema due to Vitamin D deficiency.

Vegan Diets, Vitamin D, and Problems During Pregnancy and Birth

Oxalate induces breast cancer

URL: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1747-2

Journal: BMC Cancer

Publication Date: 10/2015

Summary: Higher concentrations of oxalates were found in breast cancer tissue. Injecting oxalates into the mammary fatpad of mice induced malignant tumor formation.

Key Takeaways

Oxalates are found in plant foods such as spinach, potatoes, almonds, and cocoa. These oxalate compounds can deposit in body tissues and cause harm. This study found that breast cancer tissue had high levels of oxalates. Also, when mice had oxalates injected into their breast tissue, tumor formation occurred.

Oxalate Rich Diets May Lead To Breast Cancer

Protein-enriched diet, with the use of lean red meat, combined with progressive resistance training enhances lean tissue mass and muscle strength and reduces circulating IL-6 concentrations in elderly women: a cluster randomized controlled trial


Journal: The American Journal of Clinical Nutrition

Publication Date: 04/2014

Summary: 100 elderly women were randomized to a high protein diet supplemented with lean red meat combined with progressive resistance training versus progressive resistance training with a control diet. Lean tissue mass and strenghth increased more in the meat supplemented group. IGF-1 increase more and IL-6 decreased more in the meat supplemented group

Key Takeaways

High protein red meat containing diets lead to better strength, more lean mass, increased growth factors, and decreased inflammatory markers compared to a control diet in elderly women doing resistance training.

Losing Muscle as You Age? Try Eating Some Steak!

Status of 25(OH)D levels in pregnancy: A study from the North Eastern part of India

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/23565444/

Journal: Indian Journal of Endocrinology and Metabolism

Publication Date: 12/2012

Summary: Study of Vitamin D levels in pregnant Indian women. Vitamin D deficient women were significantly more likely to be vegetarian

Key Takeaways

Pregnant women on vegetarian diets are more likely to be vitamin D deficient, which can lead to complications with the pregnancy and development of the child.

Vegetarians Have Low Vitamin D

Relationship between animal protein intake and muscle mass index in healthy women

URL: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/relationship-between-animal-protein-intake-and-muscle-mass-index-in-healthy-women/FDD4EBFB12C8089E4FF69555FF6BB98C

Journal: British Journal of Nutrition

 Publication Date: 12/2009

Summary: 21 omnivore and 19 vegetarian women were compared. Increased animal protein intake correlated with higher muscle mass index.

Key Takeaways

Eat more animal protein to increase muscle mass

Vegetarian Diet Leads to Lack of Muscle Mass

Maternal and gestational risk factors for hypospadias

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/18709149/

Journal: Environmental Health Perspectives

Publication Date: 08/2008

Summary: A pregnancy diet lacking meat and fish appears to increase the risk of hypospadias in the offspring

Key Takeaways

Hypospadias in a congenital malformation in a child's penis that may occur due to the lack of meat and fish in the mother's diet during pregnancy.

This Can Happen To Your Child's Penis If You Don't Eat Meat While Pregnant

A maternal vegetarian diet in pregnancy is associated with hypospadias. The ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood

URL: https://www.ncbi.nlm.nih.gov/m/pubmed/10619956/

Journal: BJUI International

Publication Date: 08/2008

Summary: As vegetarians have a greater exposure to phytoestrogens than do omnivores, these results support the possibility that phytoestrogens have a deleterious effect on the developing male reproductive system.

Key Takeaways

Mothers who consume vegetarian diets high in phytoestrogens may be associated with poor development of their baby boy's penis. This abnormal development can lead to hypospadias.

Plant Based Diets Can Do What To Your Penis?

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