Peer-Reviewed Scientific Articles​

A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women


Journal: Applied Physiology, Nutrition, and Metabolism

Publication Date: 06/2007

Summary: A high-protein diet was superior to a low-fat, high-carbohydrate diet either alone or when combined with an aerobic/resistance-training program in promoting weight loss and nitrogen balance, while similarly improving body composition and risk factors for the Metabolic Syndrome in overweight and obese Canadian women.

Key Takeaways

High protein diets are superior to low-fat high carbohydrate diets at promoting weight loss, nitrogen balance, positive changes in body composition, and risk of metabolic disease

Meat and soy protein affect calcium homeostasis in healthy women


Journal: The Journal of Nutrition

 Publication Date: 07/2006

 Summary: These data indicate that when soy protein is substituted for meat protein, there is an acute decline in dietary calcium bioavailability.

Key Takeaways

Soy protein, typically used as an alternative protein source by vegans and vegetarians, has less bioavailable calcium than traditional meat products.

Dietary protein intake and renal function


Journal: Nutrition & Metabolism

Publication Date: 09/2005

Summary: This paper reviews the available evidence that increased dietary protein intake is a health concern in terms of the potential to initiate or promote renal disease. While protein restriction may be appropriate for treatment of existing kidney disease, we find no significant evidence for a detrimental effect of high protein intakes on kidney function in healthy persons after centuries of a high protein Western diet.

Key Takeaways

High protein diets have not been shown to have negative health effects in healthy people.

Protein Quantity and Quality at Levels above the RDA Improves Adult Weight Loss


Journal: Journal of the American College of Nutrition

Publication Date: 10/2004

Summary: our research suggests that increased use of high quality protein at breakfast maybe important for the metabolic advantage of a higher protein diet.

Key Takeaways

The amino acid leucine plays an important role in muscle protein synthesis. Protein intake should be at least 1.5 grams per kilogram. High quality protein consumed during breakfast is metabolically advantageous.

Animal Protein, Animal Fat, and Cholesterol Intakes and Risk of Cerebral Infarction Mortality in the Adult Health Study


Journal: Stroke

Publication Date: 05/2004

Summary: A high consumption of animal fat and cholesterol was associated with a reduced risk of cerebral infarction death in a observational study of Japanese men

Key Takeaways

A small study on Japanese men showed that higher consumption of animal fat and cholesterol led to decreased risk of stroke.

Dietary protein, calcium metabolism, and skeletal homeostasis revisited


Journal: The American Journal of Clinical Nutrition

Publication Date: 09/2003

Summary: Dietary protein intakes at and below 0.8 g/kg were associated with a probable reduction in intestinal calcium absorption sufficient to cause secondary hyperparathyroidism. The long-term consequences of these low-protein diet–induced changes in mineral metabolism are not known, but the diet could be detrimental to skeletal health. Of concern are several recent epidemiologic studies that demonstrate reduced bone density and increased rates of bone loss in individuals habitually consuming low-protein diets. Studies are needed to determine whether low protein intakes directly affect rates of bone resorption, bone formation, or both.

Key Takeaways

Protein intake less than .8g/kg led to decreased ability. for the intestine to absorb calcium. This decreased absorption was enough to stimulate the calcium sensing hormone parathyroid hormone. Parathyroid hormone acts to increase calcium levels by multiple mechanisms, but one of these is the leeching of stored calcium in the bones. Low protein diets may be associated with poor bone health due to loss of calcium.

Controlled High Meat Diets Do Not Affect Calcium Retention or Indices of Bone Status in Healthy Postmenopausal Women


Journal: Journal of Nutrition

Publication Date: 04/2003

Summary: Calcium retention was measured in postmenopausal women on both a high meat and low meat diet. There was no significant difference in calcium retention between diets

Key Takeaways

High meat diets do not lead to excess accumulation of calcium.

Characterization of meat consumption and risk of colorectal cancer in Cordoba, Argentina


Journal: Nutrition

Publication Date: 01/2003

Summary: Comparison of food frequency questionairre between patients with colorectal cancer and hospitalized control patients in Brazil. Consumption of total meat, red meat, and other types of meat were not related to increased risk of CRC. However, an increased risk of CRC was found for those consuming relatively large amounts of cold cuts and sausages and bovine viscera

Key Takeaways

Red meat and total meat consumption was not associated with increased risk of colon cancer, but increased amounts of cold cuts, sausages, and cow organs were associated with increased colon cancer.

Protein consumption and bone mineral density in the elderly : the Rancho Bernardo Study


Journal: American Journal of Epidemiology

Publication Date: 04/2002

Summary: This study supports a protective role for dietary animal protein in the skeletal health of elderly women.

Key Takeaways

Increased protein intake can lead to increases in bone mineral density in elderly women.

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