Peer-Reviewed Scientific Articles​

Lost Seasonality and Overconsumption of Plants: Risking Oxalate Toxicity

URL: https://jevohealth.com/cgi/viewcontent.cgi?article=1085&context=journal

Journal: Journal of Evolution and Health

Publication Date: 05/2018

Summary: In many plants, oxalate crystals are present. These relatively large microcrystals have the potential to inflict mechanical injury. On the other hand, ionic, soluble, and nano-crystal forms of oxalate are readily absorbed. Bioaccumulation in humans is well documented. Crystals and ionic oxalate are associated with pain and both functional and chronic disorders. Today’s many health challenges have led people to select foods purported to be healthier, many of which are high in oxalate. Modern dietary approaches have placed great emphasis on the health benefits of vegetables, nuts, and spices. Many of these are high oxalate foods that are now distributed through a global food system in which seasons have been erased, making harm from dietary oxalate more likely now than ever before.

Key Takeaways

With loss of seasonal eating patterns and increased media push of plant based foods, oxalate toxicity is more likely. Oxalates are crystals found in many plant foods such as spinach, potatoes, nuts, and spices that can cause mechanical injury in the body or deposit in tissues, which results in pain, functional, and chronic disorders.

Oxalate induces breast cancer

URL: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1747-2

Journal: BMC Cancer

Publication Date: 10/2015

Summary: Higher concentrations of oxalates were found in breast cancer tissue. Injecting oxalates into the mammary fatpad of mice induced malignant tumor formation.

Key Takeaways

Oxalates are found in plant foods such as spinach, potatoes, almonds, and cocoa. These oxalate compounds can deposit in body tissues and cause harm. This study found that breast cancer tissue had high levels of oxalates. Also, when mice had oxalates injected into their breast tissue, tumor formation occurred.

A potential pathogenic role of oxalate in autism

URL: https://www.sciencedirect.com/science/article/abs/pii/S1090379811001541

Journal: European Journal of Pediatric Neurology

Publication Date: 09/2012

Summary: Oxalates levels found to be elevated 2.5- 3 times higher in children with autistic spectrum disorder than children who do not have autistic spectrum disorder

Key Takeaways

Oxalates are crystals found in many plant foods such as spinach, potatoes, nuts, and many others that can deposit in tissues in the body and cause damage. Children with autistic spectrum disorder have 2.5-3 times higher levels of oxalates than children without these disorders.

The Effects of Vegetable and Animal Protein Diets on Calcium, Urate and Oxalate Excretion

URL:  https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1464-410X.1982.tb13602.x

Journal: British Journal of Urology

Publication Date: 12/1982

Summary: Meat eating subjects were compared to vegetarians. Higher protein intake, particulary animal protein, was linked to higher urinary calcium excretion. Higher calcium intake was linked to decreased oxalate excretion. Higher vegetable protein intake, but not meat protein intake, was linked to higher urinary oxalate excretion.

Key Takeaways

Based on urinary excretion, meat based diets were higher in calcium and lower in oxalates and vegetarian diets were higher in oxalates.

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