Better memory functioning associated with higher total and low-density lipoprotein cholesterol levels in very elderly subjects without the apolipoprotein e4 allele

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URL: https://www.ncbi.nlm.nih.gov/pubmed/18757771

Journal: American Journal of Geriatric Psychiatry

Publication Date: 09/2008

Summary: In oldest old nondemented noncarriers of the APOE4 allele, high cholesterol is associated with better memory function. Further examination of the role of APOE genotype on the association between cholesterol and cognitive performance, especially in the oldest old is warranted.

Key Takeaways

The APOE4 gene is associated with an increased risk of Alzheimer's dementia. In older individuals with the APOE4 gene, higher cholesterol levels were associated with better memory function.

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